Human Growth hormone administration within normal animals leads to muscle hypertrophy, but this muscular growth is not accompanied by increased strength ( but size definitely increased)at 2 year postinjection and increased aerobic capacity ( weight difference is no longer detectable ) and thus no significant effect of administration of growth hormone or protein was observed when compared with the control group. It has been suggested that an increased insulin resistance in skeletal muscle under normal conditions is due to inadequate insulin. In this study, we evaluated whether skeletal muscle protein synthetic ability was increased in the muscle supplemented with recombinant human growth hormone at 2 year postinjection on a muscle protein cross-section, growth hormone inhibitor drugs. In addition we also demonstrated that an increase of muscle thickness was evident by 2–3 weeks after treatment in the GHD protein group. We speculate that human growth hormone may have a beneficial effect on bone resorption induced by GH deficiency, such as bone resorption induced by deficiency in recombinant human growth hormone at the level of skeletal muscle, growth for hormone animals. However, this is still speculative and cannot be extrapolated to other tissues, growth hormone for animals.
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