These observations indicate that immune alterations do occur with anabolic steroids which are immunosuppressive when the steroid nucleus is intact and immunostimulatory with nuclear alterationsupon steroid activation (Barker et al., 2011). Other immunological observations and reports have suggested altered steroidogenic function, changes that may increase the risk of certain types of immunologic adverse event (Abraham et al., 2012a,b; Koehler et al., 2012), and alterations in gene expression of gene families known with an immunosuppressive or steroidogenic effect (Hazen et al., 2007, 2009; Abraham et al., 2012b,d). These changes in the gene(s) activated by anabolic steroids have been linked to increased immune responses to the steroid itself (Hazen et al, are anabolic steroids immunosuppressive., 2007, 2009) and may lead to the possible progression of immune dysfunction or changes (Pomerleau et al, are anabolic steroids immunosuppressive., 2012), although these are likely to remain in the distant future, are anabolic steroids immunosuppressive. It is interesting that the increased risk of autoimmune disease has been observed for both in vitro and cell culture studies with a variety of different types of anabolic steroids (Abraham et al., 2009; Hagen-Gould et al., 2007; Abouhosseinec and Abouhosseinec, 2008).
Allergy to anabolic steroids
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